RBBP4/RbAp48 Antibody (C.15200033) - BSA Free

Novus Biologicals | Catalog # NBP2-62798

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # C.15200033

Format

BSA Free
View all RBBP4 Primary Antibodies »

Product Specifications

Immunogen

Human RbAp48 protein (retinoblastoma binding protein p48)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Description

Monoclonal antibody raised in mouse against the full length human RbAp48 protein (Retinoblastomabinding protein p48) fused to GST. The antibody recognizes both RbAp48 and RbAp46.

Scientific Data Images for RBBP4/RbAp48 Antibody (C.15200033) - BSA Free

Western Blot: RBBP4/RbAp48 Antibody (C.15200033) [NBP2-62798]

Western Blot: RBBP4/RbAp48 Antibody (C.15200033) [NBP2-62798]

Western Blot: RBBP4/RbAp48 Antibody (C.15200033) [NBP2-62798] - Analysis of nuclear extracts from HeLa cells (20 ug) using the monoclonal antibody against hRbAp46/48.

Applications for RBBP4/RbAp48 Antibody (C.15200033) - BSA Free

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide and 0.05% ProClin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RBBP4

RbAp48 (UniProtKB/Swiss-Prot entry Q09028) is a component of several complexes which regulate chromatin metabolism. These include (1) the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; (2) the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; (3) the nucleosome remodelling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; (4) the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and (5) the NURF (nucleosome remodeling factor) complex. Therefore it may target chromatin assembly factors as well as chromatin remodeling factors and histone deacetylases to their histone substrates in a nucleosomal DNA dependent manner.

Long Name

Retinoblastoma Binding Protein 4

Alternate Names

CAF-1 p48, CAF-1C, NURF55, RBAP48

Gene Symbol

RBBP4

Additional RBBP4 Products

Product Documents for RBBP4/RbAp48 Antibody (C.15200033) - BSA Free

Certificate of Analysis

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Product Specific Notices for RBBP4/RbAp48 Antibody (C.15200033) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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