HRK (harakiri) is a 10 kDa pro-apoptotic member of the Bcl-2 family of apoptosis regulatory proteins. Hrk lacks significant homology to other Bcl-2 family members except for an 8-amino acid region that is similar to the BH3 domain of Bik (Bcl-2-interacting Killer). Hrk physically interacts with Bcl-2 and Bcl-xL, but not with the pro-apoptotic Bax, BAK, or Bcl-xS. Hrk regulates apoptosis by interacting selectively with survival-promoting Bcl-2 and Bcl-xL to induce cell death.
Recombinant Human Hrk Western Blot Standard Protein
R&D Systems | Catalog # WBC013
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Key Product Details
- R&D Systems E. coli-derived Recombinant Human Hrk Western Blot Standard Protein (WBC013)
- Quality control testing to verify active proteins with lot specific assays by in-house scientists
- All R&D Systems proteins are covered with a 100% guarantee
Source
E. coli
Applications
Western Blot
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Formulation, Preparation, and Storage
WBC013
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
Background: Hrk
Long Name
Harakiri
Alternate Names
activator of apoptosis harakiri, activator of apoptosis Hrk, BCL2-interacting protein, BH3-interacting domain-containing protein 3, BID3, death protein 5, DP5, HARAKIRI, harakiri, BCL2 interacting protein (contains only BH3 domain), harakiri, BCL2-interacting protein (contains only BH3 domain), Neuronal death protein DP5
Entrez Gene IDs
8739 (Human)
Gene Symbol
HRK
Additional Hrk Products
Product Documents for Recombinant Human Hrk Western Blot Standard Protein
Product Specific Notices for Recombinant Human Hrk Western Blot Standard Protein
For research use only
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
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- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars