Recombinant Human Mcl-1 Western Blot Standard Protein

Name: Recombinant Human Mcl-1 Western Blot Standard Protein
Brand: R&D Systems
SKU: WBC003
Price: 188 USD
Availability: InStock

R&D Systems | Catalog # WBC003

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

R&D Systems E. coli-derived Recombinant Human Mcl-1 Western Blot Standard Protein (WBC003)
Quality control testing to verify active proteins with lot specific assays by in-house scientists
All R&D Systems proteins are covered with a 100% guarantee

Source

Sf 21 (baculovirus)

Applications

Western Blot

View all Mcl-1 Proteins and Enzymes »

Formulation, Preparation, and Storage

WBC003

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Mcl-1

Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.

Long Name

Myeloid Cell Leukemia Sequence 1

Alternate Names

BCL2L3, Mcl1

Entrez Gene IDs

4170 (Human); 17210 (Mouse)

Gene Symbol

MCL1

Additional Mcl-1 Products

Product Documents for Recombinant Human Mcl-1 Western Blot Standard Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human Mcl-1 Western Blot Standard Protein

For research use only

Related Research Areas

Bcl-2 Proteins and Regulators

Hematopoietic Stem Cell Markers

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