Recombinant Human MMP-9 Western Blot Standard Protein

R&D Systems | Catalog # WBC018

R&D Systems
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Key Product Details

  • R&D Systems CHO-derived Recombinant Human MMP-9 Western Blot Standard Protein (WBC018)
  • Quality control testing to verify active proteins with lot specific assays by in-house scientists
  • All R&D Systems proteins are covered with a 100% guarantee

Source

CHO

Applications

Western Blot
View all MMP-9 Proteins and Enzymes »

Product Specifications

Source

Chinese Hamster Ovary cell line, CHO-derived human MMP-9 protein

SDS-PAGE

92 kDa

Reviewed Applications

Read 1 review rated 5 using WBC018 in the following applications:

Formulation, Preparation, and Storage

WBC018
Formulation
No With Carrier Product Bottling Info
Reconstitution Resuspend the lyophilized powder in 250 uL SDS-PAGE sample buffer.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: MMP-9

MMP-9 (Gelatinase B) is a metalloproteinase that degrades multiple extracellular matrix components including Gelatin, Collagens III, IV, V, and XI, Elastin, Nidogen-1, and Vitronectin. It also cleaves a variety of chemokines and growth factors (e.g. IL-1 beta, CXCL8/IL-8, CXCL7, CXCL4, CXCL1, Latent TGF-beta, membrane bound TNF-alpha, VEGF, and FGF basic), Amyloid beta peptide, Substance P, and Myelin Basic Protein. MMP-9 can trigger signaling through various transmembrane proteins or inhibit signaling by inducing their shedding from the cell surface (e.g. CD44, E-Cadherin, Integrins, ICAM-1, and CD25/IL-2 R alpha). The activity of MMP-9 is regulated by its association with the TIMP-1 protease inhibitor. Circulating levels of MMP-9 are elevated in many inflammatory disorders including intraluminal thrombus formation, atherosclerosis, Crohn’s disease, hepatitis C virus infection, colorectal cancer, and Duchenne muscular dystrophy.

Long Name

Matrix Metalloproteinase 9

Alternate Names

CLG4B, Gelatinase B, GELB, MANDP2, MMP9

Entrez Gene IDs

4318 (Human); 17395 (Mouse); 81687 (Rat); 102117693 (Cynomolgus Monkey)

Gene Symbol

MMP9

Additional MMP-9 Products

Product Documents for Recombinant Human MMP-9 Western Blot Standard Protein

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Recombinant Human MMP-9 Western Blot Standard Protein

For research use only

Citations for Recombinant Human MMP-9 Western Blot Standard Protein

Customer Reviews for Recombinant Human MMP-9 Western Blot Standard Protein (1)

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  • Recombinant Human MMP-9 Western Blot Standard Protein
    Name: Mizuho Kittaka
    Application: SDS-PAGE Control
    Verified Customer | Posted 04/12/2017
    Detected with rabbit poly anti-MMP9 antibody (ab38898)
    Recombinant Human MMP-9 Western Blot Standard Protein WBC018

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