Recombinant Human PARP Enzyme
Recombinant Human PARP Enzyme Summary
• Identification of inhibitors of PARP1 activity Quantitation of DNA Damage Investigation of PARP1 inactivation during apoptosis Western Blot Analysis
PARP1 uses NAD+ as a substrate to catalyze poly(ADP-ribosyl)ation of target proteins involved in chromatin structure and DNA metabolism. PARP1 is stimulated by DNA-strand breaks and capable of auto-ribosylation.
For research use only. Not for diagnositic use.
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