Recombinant Mouse CXCL12/SDF-1 alpha Protein

Formulations:
Catalog # Availability Size / Price Qty
460-SD-010
460-SD-050
Recombinant Mouse CXCL12/SDF-1 alpha Protein Data
2 Images
Product Details
Citations (69)
FAQs
Reviews (7)

Recombinant Mouse CXCL12/SDF-1 alpha Protein Summary

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CXCR4. The ED50 for this effect is 0.15-0.6 ng/mL. Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL). The ED50 for this effect is 3-9 ng/mL.
Source
E. coli-derived mouse CXCL12/SDF-1 alpha protein
Lys22-Lys89
Accession #
N-terminal Sequence
Analysis
Lys22
Predicted Molecular Mass
8 kDa

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

460-SD

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

460-SD/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity View Larger

Recombinant Mouse CXCL12/SDF-1 alpha (Catalog # 460-SD) chemoattracts the BaF3 mouse pro-B cells transfected with human CXCR4. The ED50for this effect is 0.15-0.6 ng/mL.

SDS-PAGE View Larger

1 μg/lane of Recombinant Mouse CXCL12/SDF-1 alpha was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 7 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CXCL12/SDF-1 alpha

SDF-1 alpha and SDF-1 beta, members of the chemokine alpha subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a human stromal cell line as cytokines that supported the proliferation of a stromal cell‑dependent pre-B-cell line, and were named Pre‑B‑Cell Growth Stimulating Factor (PBSF). SDF‑1 alpha  and SDF‑1 beta cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. Both SDF-1 alpha and SDF‑1 beta are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy‑terminus of SDF-1 beta and absent from SDF‑1 alpha. SDF‑1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF‑1/PBSF acts via the chemokine receptor CXCR4 and has been shown to be a chemoattractant for T‑lymphocytes, monocytes, pro- and pre- B cells, but not neutrophils. Mice lacking SDF-1 or CXCR4 have been found to have impaired B‑lymphopoiesis, myelopoiesis, vascular development, cardiogenesis and abnormal neuronal cell migration and patterning in the central nervous system.

References
  1. Ma, Q. et al. (1998) Proc. Natl. Acad. Sci. USA 95:9448.
  2. Zou, Y.R. et al. (1998) Nature 393:595.
  3. Tachibana, K. et al. (1998) Nature 393:591.
Entrez Gene IDs
6387 (Human); 20315 (Mouse); 493806 (Feline)
Alternate Names
CXCL12 chemokine (C-X-C motif) ligand 12; CXCL12/SDF-1 alpha; IRH; PBSF; SCYB12; SDF1 alpha; SDF1; SDF1a; SDF1B; TLSF; TPAR1

Citations for Recombinant Mouse CXCL12/SDF-1 alpha Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

69 Citations: Showing 1 - 10
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  1. CXCL12/CXCR4 signaling induced itch and pain sensation in a murine model of allergic contact dermatitis
    Authors: W Su, J Yu, Q Liu, L Ma, Y Huang
    Mol Pain, 2020;16(0):1744806920926.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  2. LncRNA Neat1 mediates miR-124-induced activation of Wnt/beta-catenin signaling in spinal cord neural progenitor cells
    Authors: Y Cui, Y Yin, Z Xiao, Y Zhao, B Chen, B Yang, B Xu, H Song, Y Zou, X Ma, J Dai
    Stem Cell Res Ther, 2019;10(1):400.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Hto, Tritiated Amino Acid Exposure and External Exposure Induce Differential Effects on Hematopoiesis and Iron Metabolism
    Authors: JM Bertho, D Kereselidz, L Manens, C Culeux, V Magneron, J Surette, M Blimkie, L Bertrand, H Wyatt, M Souidi, I Dublineau, N Priest, JR Jourdain
    Sci Rep, 2019;9(1):19919.
    Species: Mouse
    Sample Types: Plasma
    Applications: Multiplex Standard
  4. CXCR4 signaling directs Igk recombination and the molecular mechanisms of late B lymphopoiesis
    Authors: M Mandal, MK Okoreeh, DE Kennedy, M Maienschei, J Ai, KC McLean, N Kaverina, M Veselits, I Aifantis, F Gounari, MR Clark
    Nat. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Nanoparticle-modified chitosan-agarose-gelatin scaffold for sustained release of SDF-1 and BMP-2
    Authors: B Wang, Y Guo, X Chen, C Zeng, Q Hu, W Yin, W Li, H Xie, B Zhang, X Huang, F Yu
    Int J Nanomedicine, 2018;13(0):7395-7408.
    Species: Human
    Sample Types: Nanoparticles
    Applications: Bioassay
  6. The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses
    Authors: SJ Keppler, M Burbage, F Gasparrini, L Hartjes, S Aggarwal, MJ Massaad, RS Geha, A Bruckbauer, FD Batista
    Cell Rep, 2018;24(3):619-629.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. A Chimeric Antibody against ACKR3/CXCR7 in Combination with TMZ Activates Immune Responses and Extends Survival in Mouse GBM Models
    Authors: N Salazar, JC Carlson, K Huang, Y Zheng, C Oderup, J Gross, AD Jang, TM Burke, S Lewén, A Scholz, S Huang, L Nease, J Kosek, M Mittelbron, EC Butcher, H Tu, BA Zabel
    Mol. Ther., 2018;0(0):.
    Applications: Bioassay
  8. Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction
    Authors: Y Duan, E Beli, S Li Calzi, JL Quigley, RC Miller, L Moldovan, D Feng, TE Salazar, S Hazra, J Al-Sabah, KV Chalam, T Le Phuong, M Meroueh, TA Markel, MC Murray, RJ Vyas, ME Boulton, P Parsons-Wi, GY Oudit, AG Obukhov, MB Grant
    Stem Cells, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and ?1-integrin function
    Authors: V Andreani, S Ramamoorth, A Pandey, E Lupar, SL Nutt, T Lämmermann, R Grosschedl
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis
    Authors: SK Martin, S Fitter, N El Khawank, RH Grose, CR Walkley, LE Purton, MA Ruegg, MN Hall, S Gronthos, ACW Zannettino
    Sci Rep, 2018;8(1):14501.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming
    Authors: L Simula, I Pacella, A Colamatteo, C Procaccini, V Cancila, M Bordi, C Tregnago, M Corrado, M Pigazzi, V Barnaba, C Tripodo, G Matarese, S Piconese, S Campello
    Cell Rep, 2018;25(11):3059-3073.e10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms
    Authors: H Park, S Lad, K Boland, K Johnson, N Readio, G Jin, S Asfaha, KS Patterson, A Singh, X Yang, D Londono, A Singh, C Trempus, D Gordon, TC Wang, RJ Morris
    Nat Commun, 2018;9(1):5293.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. SDF-1 is an Autocrine Insulin-Desensitizing Factor in Adipocytes
    Authors: J Shin, A Fukuhara, T Onodera, S Kita, C Yokoyama, M Otsuki, I Shimomura
    Diabetes, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  14. Transmission of integrin ?7 transmembrane domain topology enables gut lymphoid tissue development
    Authors: H Sun, F Lagarrigue, AR Gingras, Z Fan, K Ley, MH Ginsberg
    J. Cell Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis
    Authors: XW Chen, TJ Yu, J Zhang, Y Li, HL Chen, GF Yang, W Yu, YZ Liu, XX Liu, CF Duan, HL Tang, M Qiu, CL Wang, H Zheng, J Yue, AM Guo, J Yang
    Oncogene, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1
    Authors: S Shukla, MA Langley, J Singh, JM Edgar, M Mohtashami, JC Zúñiga-Pfl, PW Zandstra
    Nat. Methods, 2017;14(5):531-538.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system
    Authors: K Choi, K Komurov, JS Fletcher, E Jousma, JA Cancelas, J Wu, N Ratner
    Sci Rep, 2017;7(0):43315.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Normal Thymocyte Egress, T Cell Trafficking, and CD4(+) T Cell Homeostasis Require Interactions between RGS Proteins and G?i2
    Authors: IY Hwang, C Park, K Harrison, JH Kehrl
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. The Small Rho GTPase TC10 Modulates B Cell Immune Responses
    Authors: M Burbage, SJ Keppler, B Montaner, PK Mattila, FD Batista
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Protein malnutrition promotes dysregulation of molecules involved in T cell migration in the thymus of mice infected with Leishmania infantum
    Authors: M Losada-Bar, A Umaña-Pére, S Cuervo-Esc, LR Berbert, R Porrozzi, FN Morgado, DA Mendes-da-, W Savino, M Sánchez-Gó, P Cuervo
    Sci Rep, 2017;7(0):45991.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. SDF-1?-induced dual pairs of E-selectin/ligand mediate endothelial progenitor cell homing to critical ischemia
    Sci Rep, 2016;6(0):34416.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  22. Proliferation, differentiation and migration of SCA1(-)/CD31(-) cardiac side population cells in vitro and in vivo
    Authors: Simon X Liang
    Int. J. Cardiol., 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Pannexin1 Channels Are Required for Chemokine-Mediated Migration of CD4+ T Lymphocytes: Role in Inflammation and Experimental Autoimmune Encephalomyelitis
    Authors: S Velasquez, S Malik, SE Lutz, E Scemes, EA Eugenin
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells
    Authors: Christina Schreck
    J. Exp. Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Regulation of Airway Inflammation by G-protein Regulatory Motif Peptides of AGS3 protein
    Sci Rep, 2016;6(0):27054.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Efficient Plasma Cell Differentiation and Trafficking Require Cxcr4 Desensitization
    Cell Rep, 2016;17(1):193-205.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. ADAP plays a pivotal role in CD4+ T cell activation but is only marginally involved in CD8+ T cell activation, differentiation, and immunity to pathogens
    J Leukoc Biol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization
    Authors: Valentina Cecchinato
    J. Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require ?4?1 Integrin To Migrate between the Peritoneum and Inflamed Skin
    Authors: SA Geherin, D Gómez, RA Glabman, G Ruthel, A Hamann, GF Debes
    J. Immunol, 2016;196(6):2514-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells
    Nat Commun, 2016;7(0):12719.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  31. Proplatelet formation is selectively inhibited by collagen type I via Syk-independent GPVI signaling
    J Cell Sci, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. An essential role for RGS protein/Galphai2 interactions in B lymphocyte-directed cell migration and trafficking.
    Authors: Hwang I, Park C, Harrison K, Boularan C, Gales C, Kehrl J
    J Immunol, 2015;194(5):2128-39.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFkappaB and ERK.
    Authors: Badr G, Sayed A, Abdel-Maksoud M, Mohamed A, El-Amir A, Abdel-Ghaffar F, Al-Quraishy S, Mahmoud M
    PLoS ONE, 2015;10(4):e0125340.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Engineered mesenchymal stem cells with enhanced tropism and paracrine secretion of cytokines and growth factors to treat traumatic brain injury.
    Authors: Wang Z, Wang Y, Wang Z, Gutkind J, Wang Z, Wang F, Lu J, Niu G, Teng G, Chen X
    Stem Cells, 2015;33(2):456-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention.
    Authors: Wang W, Yu S, Zimmerman G, Wang Y, Myers J, Yu V, Huang D, Huang X, Shim J, Huang Y, Xin W, Qiao P, Yan M, Xin W, Scadden D, Stanley P, Lowe J, Huang A, Siebel C, Zhou L
    Stem Cells, 2015;33(7):2280-93.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia.
    Authors: Arieta Kuksin C, Gonzalez-Perez G, Minter L
    Blood, 2015;125(13):2087-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. CXCR7 Mediates Neural Progenitor Cells Migration to CXCL12 Independent of CXCR4.
    Authors: Chen Q, Zhang M, Li Y, Xu D, Wang Y, Song A, Zhu B, Huang Y, Zheng J
    Stem Cells, 2015;33(8):2574-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. GPCR-mediated PLCbetagamma/PKCbeta/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis.
    Authors: Xu X, Gera N, Li H, Yun M, Zhang L, Wang Y, Wang Q, Jin T
    Mol Biol Cell, 2015;26(5):874-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  39. The role of some chemokines from the CXC subfamily in a mouse model of diabetic neuropathy.
    Authors: Zychowska M, Rojewska E, Pilat D, Mika J
    J Diabetes Res, 2015;2015(0):750182.
    Species: Mouse
    Sample Types: In Vivo
  40. SDF-1 enhances wound healing of critical-sized calvarial defects beyond self-repair capacity.
    Authors: Jin, Qiming, Giannobile, William
    PLoS ONE, 2014;9(5):e97035.
    Species: Mouse
    Sample Types: Complex Sample Type
    Applications: Bioassay
  41. CXCR4 is dispensable for T cell egress from chronically inflamed skin via the afferent lymph.
    Authors: Geherin, Skye A, Wilson, R Paul, Jennrich, Silke, Debes, Gudrun F
    PLoS ONE, 2014;9(4):e95626.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow.
    Authors: Beck T, Gomes A, Cyster J, Pereira J
    J Exp Med, 2014;211(13):2567-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis.
    Authors: Fujita N, Oritani K, Ichii M, Yokota T, Saitoh N, Okuzaki D, Sekine Y, Kon S, Muromoto R, Saitoh K, Yoshimura A, Matsuda T, Kanakura Y
    Eur J Immunol, 2014;44(6):1791-801.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. CCAAT/enhancer-binding protein beta expressed by bone marrow mesenchymal stromal cells regulates early B-cell lymphopoiesis.
    Authors: Yoshioka S, Miura Y, Yao H, Satake S, Hayashi Y, Tamura A, Hishita T, Ichinohe T, Hirai H, Takaor-Kondo A, Maekawa T
    Stem Cells, 2014;32(3):730-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. CXCR4 chemokine receptor signaling mediates pain in diabetic neuropathy.
    Authors: Menichella D, Abdelhak B, Ren D, Shum A, Frietag C, Miller R
    Mol Pain, 2014;10(0):42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations.
    Authors: Januszyk M, Sorkin M, Glotzbach J, Vial I, Maan Z, Rennert R, Duscher D, Thangarajah H, Longaker M, Butte A, Gurtner G
    Diabetes, 2014;63(9):3047-56.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Development of central nervous system autoimmunity is impaired in the absence of Wiskott-Aldrich syndrome protein.
    Authors: Bosticardo, Marita, Musio, Silvia, Fontana, Elena, Angiari, Stefano, Draghici, Elena, Constantin, Gabriela, Poliani, Pietro L, Pedotti, Rosetta, Villa, Anna
    PLoS ONE, 2014;9(1):e86942.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease.
    Authors: Graham K, Zhang J, Lewen S, Burke T, Dang T, Zoudilova M, Sobel R, Butcher E, Zabel B
    PLoS ONE, 2014;9(12):e112925.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. alphaPIX RhoGEF supports positive selection by restraining migration and promoting arrest of thymocytes.
    Authors: Korthals M, Schilling K, Reichardt P, Mamula D, Schluter T, Steiner M, Langnase K, Thomas U, Gundelfinger E, Premont R, Tedford K, Fischer K
    J Immunol, 2014;192(7):3228-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.
    Authors: Suga H, Rennert R, Rodrigues M, Sorkin M, Glotzbach J, Januszyk M, Fujiwara T, Longaker M, Gurtner G
    Stem Cells, 2014;32(5):1347-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches.
    Authors: Roy, Lopamudr, Sahraei, Mahnaz, Schettini, Jorge L, Gruber, Helen E, Besmer, Dahlia M, Mukherjee, Pinku
    BMC Cancer, 2014;14(0):225.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Control of lymphocyte egress from lymph nodes through beta2-adrenergic receptors.
    Authors: Nakai A, Hayano Y, Furuta F, Noda M, Suzuki K
    J Exp Med, 2014;211(13):2583-98.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Mammalian diaphanous-related formin 1 regulates GSK3beta-dependent microtubule dynamics required for T cell migratory polarization.
    Authors: Dong B, Zhang S, Gao W, Su H, Chen J, Jin F, Bhargava A, Chen X, Jorgensen L, Alberts A, Zhang J, Siminovitch K
    PLoS ONE, 2013;8(11):e80500.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Early differentiated CD138(high) MHCII+ IgG+ plasma cells express CXCR3 and localize into inflamed kidneys of lupus mice.
    Authors: Lacotte S, Decossas M, Le Coz C, Brun S, Muller S, Dumortier H
    PLoS ONE, 2013;8(3):e58140.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Rgs13 constrains early B cell responses and limits germinal center sizes.
    Authors: Hwang I, Hwang K, Park C, Harrison K, Kehrl J
    PLoS ONE, 2013;8(3):e60139.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy.
    Authors: Scherz-Shouval R, Santagata S, Mendillo M, Sholl L, Ben-Aharon I, Beck A, Dias-Santagata D, Koeva M, Stemmer S, Whitesell L, Lindquist S
    Cell, 2013;158(3):564-78.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Sonic hedgehog mediates the proliferation and recruitment of transformed mesenchymal stem cells to the stomach.
    Authors: Donnelly J, Chawla A, Houghton J, Zavros Y
    PLoS ONE, 2013;8(9):e75225.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Moesin controls clathrin-mediated S1PR1 internalization in T cells.
    Authors: Nomachi, Akira, Yoshinaga, Masanori, Liu, Jaron, Kanchanawong, Pakorn, Tohyama, Kiyoshi, Thumkeo, Dean, Watanabe, Takeshi, Narumiya, Shuh, Hirata, Takako
    PLoS ONE, 2013;8(12):e82590.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. PI3-kinase gamma promotes Rap1a-mediated activation of myeloid cell integrin alpha4beta1, leading to tumor inflammation and growth.
    Authors: Schmid M, Franco I, Kang S, Hirsch E, Quilliam L, Varner J
    PLoS ONE, 2013;8(4):e60226.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  60. G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis.
    Authors: Raghuwanshi S, Smith N, Rivers E, Thomas A, Sutton N, Hu Y, Mukhopadhyay S, Chen X, Leung T, Richardson R
    J Immunol, 2013;190(10):5329-36.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: ELISA (Capture)
  61. Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration.
    Authors: Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I
    Eur. J. Immunol., 2012;42(5):1226-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization.
    Authors: Ippagunta SK, Malireddi RK, Shaw PJ
    Nat. Immunol., 2011;12(10):1010-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Mucosa-associated epithelial chemokine/CCL28 expression in the uterus attracts CCR10+ IgA plasma cells following mucosal vaccination via estrogen control.
    Authors: Cha HR, Ko HJ, Kim ED
    J. Immunol., 2011;187(6):3044-52.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  64. CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1.
    Authors: Kollmar O, Rupertus K, Scheuer C, Nickels RM, Haberl GC, Tilton B, Menger MD, Schilling MK
    Int. J. Cancer, 2010;126(6):1302-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice.
    Authors: Lin Y, Xu L, Jin H, Zhong Y, Di J, Lin QD
    Fertil. Steril., 2009;91(6):2687-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells.
    Authors: Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N
    J. Exp. Med., 2008;205(11):2643-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Pulmonary stromal-derived factor-1 expression and effect on neutrophil recruitment during acute lung injury.
    Authors: Petty JM, Sueblinvong V, Lenox CC, Jones CC, Cosgrove GP, Cool CD, Rai PR, Brown KK, Weiss DJ, Poynter ME, Suratt BT
    J. Immunol., 2007;178(12):8148-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  68. CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy.
    Authors: Bhangoo SK, Ren D, Miller RJ, Chan DM, Ripsch MS, Weiss C, McGinnis C, White FA
    Brain Behav. Immun., 2007;21(5):581-91.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  69. The role of CCL21 in recruitment of T-precursor cells to fetal thymi.
    Authors: Ueno T, Kuse S, Saito F, Nitta T, Kakiuchi T, Hollander GA, Takahama Y
    Blood, 2005;105(1):31-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

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Reviews for Recombinant Mouse CXCL12/SDF-1 alpha Protein

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Recombinant Mouse CXCL12/SDF-1 alpha Protein
By Anonymous on 11/04/2019
Application: Characterization prior to use in downstream assay.
Reason for Rating: MW matches theoretical by LC/MS.

Recombinant Mouse CXCL12/SDF-1 alpha Protein
By Anonymous on 04/15/2019
Application: SDS-PAGE Control

Recombinant Mouse CXCL12/SDF-1 alpha Protein
By Anonymous on 01/28/2019
Application: Cell migration/motility

Recombinant Mouse CXCL12/SDF-1 alpha Protein
By Anonymous on 01/28/2019
Application: Enzymatic activity in vitro

Recombinant Mouse CXCL12/SDF-1 alpha Protein
By Anonymous on 12/16/2016
Application: Cell migration/motility

Recombinant Mouse CXCL12/SDF-1 alpha Protein
By Anonymous on 08/03/2016
Application: Cell migration/motility

Recombinant Mouse CXCL12/SDF-1 alpha Protein
By Anonymous on 05/17/2016
Application: In vitro bioactivity in cell culture