Canine Renin ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) %CV 10 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) %CV 12 (example only; lot dependent)

Recovery for Canine Renin ELISA Kit (Colorimetric)

Kit Contents for Canine Renin ELISA Kit (Colorimetric)

• Assay Diluent A
• Assay Diluent B
• Detection Reagent A
• Detection Reagent B
• Instruction manual
• Plate sealer for 96 wells
• Pre-coated ready to use 96-well strip plate
• Standard
• Standard Diluent
• Stop Solution
• TMB Substrate
• Wash Buffer (30 x concentrate)

Preparation and Storage

Background: Renin

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

Additional Renin Products

• All Products for Renin
• Renin ELISA Kits
• Renin Lysates
• Renin Primary Antibodies
• Renin Proteins and Enzymes
• Renin Supplemental Kits and Reagents

Product Documents for Canine Renin ELISA Kit (Colorimetric)