Chemical Name: Ethyl [2-amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]carbamate
Biological ActivityRetigabine is a KV7 (KCNQ) channel activator (EC50 values are 0.6 - 100 μM for KV7.1 - KV7.5). Anticonvulsant. Orally bioavailable.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Retigabine: chemical synthesis to clinical application.
Blackburn-Munro et al.
CNS Drug Rev., 2005;11:1
Citation for Retigabine
The citations listed below are publications that use Tocris products. Selected citations for Retigabine include:
1 Citation: Showing 1 - 1
Molecular expression and pharmacological evidence for a functional role of kv7 channel subtypes in Guinea pig urinary bladder smooth muscle.
Authors: Afeli Et al.
PLoS One 2013;8:e75875
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