RGDS peptide

Tocris Bioscience | Catalog # 3498

Integrin binding sequence; inhibits integrin receptor function
Tocris Bioscience

Key Product Details

Description

Integrin binding sequence; inhibits integrin receptor function
View all Integrin Receptor Inhibitors »

Product Description

RGDS peptide is an integrin binding sequence that inhibits integrin receptor function. Decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. Promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro.

Product Specifications for RGDS peptide

Molecular Weight

433.42

Formula

C15H27N7O8

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

91037-65-9

PubChem ID

107775

InChI Key

NNRFRJQMBSBXGO-CIUDSAMLSA-N

SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 36 publications citing the usage of this product.

Product Documents for RGDS peptide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RGDS peptide

For research use only

Customer Reviews for RGDS peptide (2)

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  • Cell cultures with ECM proteins, integrin blockade and In vitro drug treatments
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: rat astroglioma C6 cells
    Verified Customer | Posted 03/24/2020
    Co-incubated with RGDS 10 µg/ml
    RGDS peptide 3498
  • Mitochondrial bioenergetics measurements by reagent screen
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: mouse brain endothelioma cell line
    Verified Customer | Posted 03/15/2020
    100 μg/ml
    RGDS peptide 3498

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