RIN1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-30812

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

His-tagged recombinant human RIN1 protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for RIN1 Antibody - BSA Free

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody detects recombinant Rin protein expressed in HEK-293 cells by Western blot analysis. Shows minimal cross-reactivity with Rit protein and other Ras proteins..

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

Phosphate buffered saline

Format

BSA Free

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RIN1

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis

Alternate Names

Ras and Rab interactor 1, ras inhibitor 1, Ras inhibitor JC99, ras inhibitor RIN1, Ras interaction/interference protein 1

Gene Symbol

RIN1

Additional RIN1 Products

Product Documents for RIN1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for RIN1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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