Dual cholinesterase inhibitor (ChEI); inhibits both butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). Brain penetrant.
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All Tocris products are intended for laboratory research use only.
The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by two series of novel carbamates.
Groner et al.
Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine.
Luo et al.
New acetylcholinesterase inhibitors for Alzheimer's disease.
Mehta et al.
Int.J.Alzheimers Dis., 2012;:Epub 2011
Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons.
Bailey et al.
PLoS One, 2011;6:e21954
The citations listed below are publications that use Tocris products. Selected citations for Rivastigmine tartrate include:
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