Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Biological ActivityRo 90-7501 is an inhibitor of amyloid β42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC50 = 2 μM).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.
Bohrmann et al.
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