Catalog Number: 2408
Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Biological Activity
Inhibitor of amyloid β42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC50 = 2 μM).
Technical Data
  • M.Wt:
    340.39
  • Formula:
    C20H16N6
  • Solubility:
    Soluble to 10 mM in 1eq. HCl and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    293762-45-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.
    Bohrmann et al.
    J.Struct.Biol., 2000;130:232

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