Potent VGlut and vesicular monoamine transporter (VMAT) inhibitor (Ki
values are 19 and 64 nM, respectively). Inhibits ATP dependent vesicular glutamate uptake (IC50
= 37 nM) and diminishes the amount of exocytotically released glutamate in synaptosomes. Decreases synaptic transmission in the dentate gyrus. Also stains exposed epithelium in the eye. Cell permeable.
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Rose Bengal analogs and vesicular glutamate transporters (VGLUTs).
Pietrancosta et al.
Inhibition of vesicular glutamate storage and exocytotic release by Rose Bengal.
Ogita et al.
J Neurochem., 2001;77:34
Modulation of hippocampal synaptic transmission by the kynurenine pathway member xanthurenic acid and other VGLUT inhibitors. Neuropsychopharmacology.
Neale et al.
What is actually stained by rose bengal?
Feenstra et al.