RP 001 hydrochloride

Catalog # Availability Size / Price Qty
4289/10
4289/50
RP 001 hydrochloride | CAS No. 1781880-34-9 | Sphingosine-1-phosphate Receptor Agonists
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Description: Potent S1P1 agonist

Chemical Name: N-[4-[5-[3-Cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine hydrochloride

Purity: ≥98%

Product Details
Citations (1)
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Reviews

Biological Activity

Potent agonist of S1P1 receptors (EC50 = 9 pM). Induces internalization and polyubiquitination of S1P1 in vitro. Selective for S1P1 over S1P2 - S1P4.

Technical Data

M.Wt:
468.93
Formula:
C24H24N4O4.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1781880-34-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Actions of a picomolar short-acting S1P1 agonist in S1P1-eGFP knock-in mice.
    Cahalan et al.
    Nat.Chem.Biol., 2011;7:254

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Citation for RP 001 hydrochloride

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