RP 001 hydrochloride
Chemical Name: N-[4-[5-[3-Cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine hydrochloride
Biological ActivityPotent agonist of S1P1 receptors (EC50 = 9 pM). Induces internalization and polyubiquitination of S1P1 in vitro. Selective for S1P1 over S1P2 - S1P4.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Actions of a picomolar short-acting S1P1 agonist in S1P1-eGFP knock-in mice.
Cahalan et al.
Citation for RP 001 hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for RP 001 hydrochloride include:
1 Citation: Showing 1 - 1
RP001 hydrochloride improves neurological outcome after subarachnoid hemorrhage.
Authors: Li Et al.
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VersaClone cDNA Plasmids
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