RP 001 hydrochloride

Tocris Bioscience | Catalog # 4289

Potent S1P1 agonist
Tocris Bioscience

Key Product Details

Description

Potent S1P1 agonist
View all Sphingosine-1-phosphate Receptor Agonists »

Product Description

RP 001 hydrochloride is a potent agonist of S1P1 receptors (EC50 = 9 pM). Induces internalization and polyubiquitination of S1P1 in vitro. Selective for S1P1 over S1P2 - S1P4.

Product Specifications for RP 001 hydrochloride

Molecular Weight

468.93

Formula

C24H24N4O4.HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[4-[5-[3-Cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine hydrochloride

CAS Number

1781880-34-9

PubChem ID

90488927

InChI Key

ZHPGSGYEFGEZAL-UHFFFAOYSA-N

SMILES

CC(C)OC1=C(C#N)C=C(C2=NC(C3=C(CCC4NCCC(O)=O)C4=CC=C3)=NO2)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 43.25 100

Preparing Stock Solutions for RP 001 hydrochloride

The following data is based on the product molecular weight 468.93.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.13 mL 10.66 mL 21.33 mL
5 mM 0.43 mL 2.13 mL 4.27 mL
10 mM 0.21 mL 1.07 mL 2.13 mL
50 mM 0.04 mL 0.21 mL 0.43 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for RP 001 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RP 001 hydrochloride

For research use only

Related Research Areas

Bioactive Lipids and Receptors

Citations for RP 001 hydrochloride

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