RP 001 hydrochloride
Chemical Name: N-[4-[5-[3-Cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine hydrochloride
Biological ActivityRP 001 hydrochloride is a potent agonist of S1P1 receptors (EC50 = 9 pM). Induces internalization and polyubiquitination of S1P1 in vitro. Selective for S1P1 over S1P2 - S1P4.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Actions of a picomolar short-acting S1P1 agonist in S1P1-eGFP knock-in mice.
Cahalan et al.
Citation for RP 001 hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for RP 001 hydrochloride include:
1 Citation: Showing 1 - 1
RP001 hydrochloride improves neurological outcome after subarachnoid hemorrhage.
Authors: Li Et al.
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