Rp-8-pCPT-cGMPS sodium

Catalog # Availability Size / Price Qty
5524/1
Protein Kinase G Inhibitors Small Molecule
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Description: PKG inhibitor

Chemical Name: 8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3',5'-[hydrogen [P(R)]-phosphorothioate] sodium

Purity: ≥99%

Product Details
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Biological Activity

PKG inhibitor (Ki values are 0.45, 0.5 and 0.7 μM for PKGIβ, PKGIα and PKGII respectively). Exhibits selectivity for PKG over PKA and Epac-1. Reduces LTP in hippocampal slices in vitro.

Technical Data

M.Wt:
525.86
Formula:
C16H14ClN5NaO6PS2
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
208445-07-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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