Rp-8-pCPT-cGMPS sodium

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Rp-8-pCPT-cGMPS sodium | CAS No. 208445-07-2 | Protein Kinase G Inhibitors
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Description: PKG inhibitor

Chemical Name: 8-[(4-Chlorophenyl)thio]-guanosine-cyclic 3',5'-[hydrogen [P(R)]-phosphorothioate] sodium

Purity: ≥99%

Product Details
Citations (1)

Biological Activity

Rp-8-pCPT-cGMPS sodium is a PKG inhibitor (Ki values are 0.45, 0.5 and 0.7 μM for PKGIβ, PKGIα and PKGII respectively). Exhibits selectivity for PKG over PKA and Epac-1. Reduces LTP in hippocampal slices in vitro.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for Rp-8-pCPT-cGMPS sodium

The citations listed below are publications that use Tocris products. Selected citations for Rp-8-pCPT-cGMPS sodium include:

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