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3 results for "Protein Kinase G Inhibitors" in Products
Protein Kinase G Inhibitors
Protein kinase G (PKG) is a cyclic GMP-dependent protein serine/threonine kinase that phosphorylates a variety of biological targets. There are two subtypes of PKG: PKG1 and PKG2. Due to alternative exon splicing two isoforms of PKG1, PKG1α and PKG1β, exist.
PKG1 and PKG2 are expressed in different cell types, with PKG1 at its highest concentrations in smooth muscle cells and platelets, whilst PKG2 is most abundant in the brain, lungs and intestinal mucosa. PKGs exist as antiparallel ...
Selective protein kinase G inhibitor
| Chemical Name: | (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, methyl ester |
| Purity: | ≥95% |
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Protein kinase G inhibitor
| Chemical Name: | 2-Bromo-3,4-dihydro-3-[3,5-O-[(R)-mercaptophosphinylidene]-β-D-ribofuranosyl]-6-phenyl-9H-Imidazo[1,2-a]purin-9-one sodium salt |
| Purity: | ≥98% |
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Potent and selective PKG2 inhibitor
| Chemical Name: | 4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine |
| Purity: | ≥98% |
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