Catalog Number: 1990
Chemical Name: (R,R)-5,11-Diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol
Biological Activity
Non-steroidal, selective estrogen receptor ligand; agonist at ERα receptor (Ki = 9.0 nM) and antagonist at ERβ receptor (Ki = 3.6 nM).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-α or estrogen receptor-β.
    Sun et al.
    Endocrinology, 1999;140:800
  2. Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-α and estrogen receptor-β: correlations with biological character and distinct differences among SRC coactivator family members.
    Kraichely et al.
    Endocrinology, 2000;141:3534
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