RS 100329 hydrochloride

  ( 3 citations )    
Product Datasheet
Catalog Number:1325
Chemical Name:5-Methyl-3-[3-[3-[4-[2-(2,2,2,-trifluroethoxy)phenyl]-1-piperazinyl]propyl]-2,4-(1H,3H)-pyrimidinedione hydrochloride
Product Details
Citations (3)
Supplemental Products
Reviews
Biological Activity
Subtype-selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors). Displays 126- and 50-fold selectivity over human α1B and α1D receptors respectively. Active in vivo.
Technical Data
  • M.Wt:
    462.89
  • Formula:
    C20H25F3N4O3.HCl
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    1215654-26-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Roche Bioscience
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for RS 100329 hydrochloride include:

3 Citations: Showing 1 - 3
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  1. Identification of a new pharmacological activity of the phenylpiperazine derivative naftopidil: tubulin-binding drug.
    Authors: Ishii and Sugimura
    Front Cell Neurosci  2015;8:42618
  2. High vascular tone of mouse femoral arteries in vivo is determined by sympathetic nerve activity via α1A- and α1D-adrenoceptor subtypes.
    Authors: Zacharia Et al.
    PLoS One  2013;8:e65969
  3. Sympathectomy reveals alpha 1A- and alpha 1D-adrenoceptor components to contractions to noradrenaline in rat vas deferens.
    Authors: Cleary Et al.
    Br J Pharmacol  2004;143:745

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