RU 28318, potassium salt

Tocris Bioscience | Catalog # 1672

Potent, selective mineralocorticoid receptor antagonist
Tocris Bioscience
Discontinued Product
1672 has been discontinued. View all Mineralocorticoid Receptor Antagonists products.

Key Product Details

Description

Potent, selective mineralocorticoid receptor antagonist

Alternative Names

Oxprenoate potassium
View all Mineralocorticoid Receptor Antagonists »

Product Description

RU 28318, potassium salt is a potent and selective antagonist for the mineralocorticoid receptor (MR). Inhibits aldosterone production and secretion, and selectively decreases ex-vivo MR binding in the hippocampus of adrenalectomised rats. Also decreases blood pressure in female rats following central administration in vivo.

Product Specifications for RU 28318, potassium salt

Molecular Weight

440.66

Formula

C25H37O4K

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

(7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid, potassium salt

CAS Number

76676-34-1

PubChem ID

23677972

InChI Key

HXJITUGMCJCKCE-UYOQDFFISA-M

SMILES

[K+].[H][C@@]12CC[C@@](O)(CCC([O-])=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](CCC)CC2=CC(=O)CC[C@]12C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 44.07 100

Preparing Stock Solutions for RU 28318, potassium salt

The following data is based on the product molecular weight 440.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.27 mL 11.35 mL 22.69 mL
5 mM 0.45 mL 2.27 mL 4.54 mL
10 mM 0.23 mL 1.13 mL 2.27 mL
50 mM 0.05 mL 0.23 mL 0.45 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for RU 28318, potassium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RU 28318, potassium salt

For research use only

Citations for RU 28318, potassium salt

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