Ruthenium-bipyridine-triphenylphosphine caged GABA
(Cat. No. 0344) that is excited by visible wavelengths. Provides greater tissue penetration, less phototoxicity, faster photorelease kinetics and better spatial resolution than UV light-sensitive caged compounds. Produces GABA receptor-mediated currents in pyramidal neurons in vitro
and displays no effect on endogenous GABAergic or glutamatergic transmission at concentrations effective for uncaging.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold under licence from Columbia University
A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage.
Zayat et al.
Photorelease of GABA with visible light using an inorganic caging group.
Rial Verde et al.
Front.Neural Circuits, 2008;2:2
The citations listed below are publications that use Tocris products. Selected citations for RuBi-GABA include:
Showing Results 1 - 1 of 1