Biological ActivityGABA is a GABA receptor agonist and endogenous inhibitory neurotransmitter. Caged RuBi GABA is also available (Cat. No. 3400).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
GABA, bicuculline and central inhibition.
Curtis et al.
GABA: a dominant transmitter in the hypothalamus.
Decavel and van den Pol
GABAC receptors: relatively simple transmitter-gated ion channels?
GABA and its receptors in the spinal cord.
Malcangio and Bowery
Citations for GABA
The citations listed below are publications that use Tocris products. Selected citations for GABA include:
19 Citations: Showing 1 - 10
Facilitation and inhibition of firing activity and N-methyl-D-aspartate-evoked responses of CA1 hippocampal pyramidal cells by alpha7 nicotinic acetylcholine receptor selective compounds in vivo.
Authors: Bali Et al.
Sci Rep 2019;9:9324
Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.
Authors: Nakano Et al.
Cell Rep 2019;27:860
Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support.
Authors: Garcia Et al.
Front Neurosci 2019;13:669
Structure of a human synaptic GABAA receptor.
The medullary dorsal reticular nucleus as a relay for descending pronociception induced by the mGluR5 in the rat infralimbic cortex.
FRET-based sensors unravel activation and allosteric modulation of the GABAB receptor.
Authors: Lecat-Guillet Et al.
Cell Chem Biol 2017;24(3):360
Increased GABAB receptor signaling in a rat model for schizophrenia
Authors: Selten Et al.
Scientific Reports 2016;6:34240
γ-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains.
Authors: Brown Et al.
J Biol Chem 2016;291:13926
Regulation of action potential waveforms by axonal GABAA receptors in cortical pyramidal neurons.
Authors: Xia Et al.
PLoS One 2014;9:e100968
Generation of induced neuronal cells by the single reprogramming factor ASCL1.
Authors: Chanda Et al.
Eur J Neurosci 2014;3:282
Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.
Authors: Diógenes Et al.
Cereb Cortex 2014;24:67
Membrane potential measurements of isolated neurons using a voltage-sensitive dye.
Authors: Fairless Et al.
PLoS One 2013;8:e58260
GABA(A) receptors can initiate the formation of functional inhibitory GABAergic synapses.
Authors: Fuchs Et al.
Evid Based Complement Alternat Med 2013;38:3146
GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium.
Authors: Ring Et al.
PLoS One 2012;7:e36874
Voluntary exercise offers anxiolytic potential and amplifies galanin gene expression in the locus coeruleus of the rat.
Authors: Sciolino Et al.
Behav Brain Res 2012;233:191
Identification and modulation of voltage-gated Ca2+ currents in zebrafish Rohon-Beard neurons.
Authors: Won Et al.
J Neurophysiol 2011;105:442
Autonomous initiation and propagation of action potentials in neurons of the subthalamic nucleus.
Authors: Atherton Et al.
J Physiol 2008;586:5679
GABA regulates dendritic growth by stabilizing lamellipodia in newly generated interneurons of the olfactory bulb.
Authors: Gascon Et al.
J Neurosci 2006;26:12956
Investigations into the mechanism of action of the new anticonvulsant retigabine. Interaction with GABAergic and glutamatergic neurotransmission and with voltage gated ion channels.
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