Catalog Number: 3574
Chemical Name: (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-(S)-1-aminopropane-1,3-dicarboxylic acid ruthenium(2+) complex sodium hexafluorophosphate salt
Biological Activity
Ruthenium-bipyridine-trimethylphosphine caged glutamate that can be excited by visible wavelengths and releases glutamate after one- or two-photon excitation. Has high quantum efficiency and can be used at low concentrations, partly avoiding blockade of GABAergic transmission seen with other caged glutamate compounds. Displays high spatial resolution and generates excitatory responses in individual dendritic spines with physiological kinetics.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 20 mM in water
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under licence from Columbia University
Background References
  1. RuBi-Glutamate: two-photon and visible-light photoactivation of neurons and dendritic spines.
    Fino et al.
    Front.Neural Circuits, 2009;3:1
  2. A fast ruthenium polypyridine cage complex photoreleases glutamate with visible or IR light in one and two photon regimes.
    Salierno et al.
    J.Inorg.Biochem., 2010;104:418

The citations listed below are publications that use Tocris products. Selected citations for RuBi-Glutamate include:

Showing Results 1 - 1 of 1

  1. μ-Opioid Receptor-Mediated Inhibition of Intercalated Neurons and Effect on Synaptic Transmission to the Central Amygdala.
    Authors: Blaesse Et al.
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