RuBi-Glutamate

Tocris Bioscience | Catalog # 3574

Caged glutamate; excited by visible wavelengths
Tocris Bioscience

Key Product Details

Description

Caged glutamate; excited by visible wavelengths
View all Glutamate Receptor Compounds »

Product Description

RuBi-Glutamate is a ruthenium-bipyridine-trimethylphosphine caged glutamate that can be excited by visible wavelengths and releases glutamate after one- or two-photon excitation. Has high quantum efficiency and can be used at low concentrations, partly avoiding blockade of GABAergic transmission seen with other caged glutamate compounds. Displays high spatial resolution and generates excitatory responses in individual dendritic spines with physiological kinetics.

MNI-caged-L-glutamate (Cat. No. 1490) also available.

Licensing Information

Sold under licence from Columbia University

Product Specifications for RuBi-Glutamate

Molecular Weight

970.54

Formula

C28H32N5O4PRu.2NaPF6

Storage

Store at -20°C

Chemical Name

(bis(2,2'-Bipyridine-N,N')trimethylphosphine)-(S)-1-aminopropane-1,3-dicarboxylic acid ruthenium(2+) complex sodium hexafluorophosphate salt

CAS Number

2417096-44-5

PubChem ID

90488860

InChI Key

SQQVSHWHIPVYSZ-UHFFFAOYSA-L

SMILES

[Na+].[Na+].[Ru++].CP(C)C.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.NC(CCC([O-])=O)C([O-])=O.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CN=C(C=C1)C1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 19.41 20

Preparing Stock Solutions for RuBi-Glutamate

The following data is based on the product molecular weight 970.54.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 5.15 mL 25.76 mL 51.52 mL
1 mM 1.03 mL 5.15 mL 10.30 mL
2 mM 0.52 mL 2.58 mL 5.15 mL
10 mM 0.10 mL 0.52 mL 1.03 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 28 publications citing the usage of this product.

Product Documents for RuBi-Glutamate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RuBi-Glutamate

For research use only

Customer Reviews for RuBi-Glutamate (1)

5 out of 5
1 Customer Rating
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

Have you used RuBi-Glutamate?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Customer Images

Showing  1 - 1 of 1 review Showing All
Filter By:
Clear Filters X
  • Highly recommend.
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: Periaqueductal gray
    Verified Customer | Posted 06/01/2020
    Light sensitive.
    Recording from a DA neuron in the periaqueductal gray. A 6 x 6 grid was used to locally uncage Rubi-glutamate (300 micromolar) in an area surrounding the neuron. Representative trace showing the responses to each focal stimulation in current-clamp mode.
    RuBi-Glutamate 3574

There are no reviews that match your criteria.

Showing  1 - 1 of 1 review Showing All