Ruthenium Red

  ( 14 citations )    
Product Datasheet
Catalog Number:1439
Chemical Name:Ammoniated ruthenium oxychloride
Product Details
Citations (14)
Reviews
Biological Activity
Blocks Ca2+ uptake and release from mitochondria, and Ca2+ release from ryanodine-sensitive intracellular stores. Also blocks cell membrane-located capsaicin-activated cation channels (IC50 = 14 nM) and voltage-sensitive Ca2+ channels to inhibit neurotransmitter release.
Technical Data
  • M.Wt:
    786.35
  • Formula:
    H42N14O2Ru3Cl6
  • Solubility:
    Soluble to 10 mM in water
  • Storage:
    Store at RT
  • CAS No:
    11103-72-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Ruthenium Red include:

14 Citations: Showing 1 - 10
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  1. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides.
    Authors: Ferdek Et al.
    Cell.Death.Dis.  2017;8:e2640
  2. Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides
    Authors: Russo Et al.
    The Journal of Immunology  2016;197:1353
  3. Hypotonic stress induces RANKL via transient receptor potential melastatin 3 (TRPM3) and vaniloid 4 (TRPV4) in human PDL cells.
    Authors: Son Et al.
    J Dent Res  2015;94:473
  4. Alterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction.
    Authors: Shi Et al.
    Proc Natl Acad Sci U S A  2015;21:4852
  5. Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with Isoproterenol.
    Authors: Merino Et al.
    Neuroreport  2015;10:e0132884
  6. Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage.
    Authors: Lee Et al.
    PLoS One  2014;111:E5114
  7. Sensory nerve terminal mitochondrial dysfunction activates airway sensory nerves via transient receptor potential (TRP) channels.
    Authors: Nesuashvili Et al.
    Mol Pharmacol  2013;83:1007
  8. Rapid Glucocorticoid-Induced Activation of TRP and CB1 Receptors Causes Biphasic Modulation of Glutamate Release in Gastric-Related Hypothalamic Preautonomic Neurons.
    Authors: Boychuk Et al.
    Front Neurosci  2013;7:3
  9. Small molecule positive allosteric modulation of TRPV1 activation by vanilloids and acidic pH.
    Authors: Kaszás Et al.
    J Neurosci  2012;340:152
  10. TRPV4 channels mediate the infrared laser-evoked response in sensory neurons.
    Authors: Albert Et al.
    J Neurophysiol  2012;107:3227
  11. TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles.
    Authors: Li Et al.
    Environ Health Perspect  2011;119:784
  12. Ca2+ influx through mechanosensitive channels inhibits neurite outgrowth in opposition to other influx pathways and release from intracellular stores.
    Authors: Jacques-Fricke Et al.
    World J Gastroenterol  2006;26:5656
  13. Opioid-like actions of neuropeptide Y in rat substantia gelatinosa: Y1 suppression of inhibition and Y2 suppression of excitation.
    Authors: Moran Et al.
    J Neurophysiol  2004;92:3266
  14. Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons.
    Authors: Melis Et al.
    J Neurosci  2004;24:10707
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