S 07662
Chemical Name: N-[(2-Methyl-3-benzofuranyl)methyl]-N'-(2-thienylmethyl)urea
Purity: ≥98%
Biological Activity
S 07662 is an inverse agonist of the constitutive androstane receptor (CAR). Inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Suppresses CITCO-induced CYP2B6 gene expression in human primary hepatocytes.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists.
Küblbeck et al.
Mol.Pharm., 2011;8:2424
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