(S)-3,4-DCPG

  ( 1 citations )    
Product Datasheet
Catalog Number:1302
Alternate Names:UBP 1109
Chemical Name:(S)-3,4-Dicarboxyphenylglycine
Product Details
Citations (1)
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Reviews
Biological Activity
Potent, selective mGlu8a agonist (EC50 = 31 nM). Displays > 100-fold selectivity over mGlu1-7 and displays little or no activity at NMDA and kainate receptors. Increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo. Also potent anticonvulsant in mice in vivo.

Caged (S)-3,4-DCPG, Racemate and R-enantiomer also available.

Technical Data
  • M.Wt:
    239.18
  • Formula:
    C10H9NO6
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >98
  • Storage:
    Desiccate at RT
  • CAS No:
    201730-11-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (S)-3,4-DCPG include:

1 Citations: Showing 1 - 1

  1. Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata.
    Authors: Broadstock Et al.
    Br J Pharmacol  2012;165:1034

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