(S)-3,4-DCPG

Catalog # Availability Size / Price Qty
1302/10
1302/50
Cat.No. 1302 - (S)-3,4-DCPG | C10H9NO6 | CAS No. 201730-11-2
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Description: Potent and selective mGlu8a agonist
Alternative Names: UBP 1109

Chemical Name: (S)-3,4-Dicarboxyphenylglycine

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Potent, selective mGlu8a agonist (EC50 = 31 nM). Displays > 100-fold selectivity over mGlu1-7 and displays little or no activity at NMDA and kainate receptors. Increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo. Also potent anticonvulsant in mice in vivo.

Caged (S)-3,4-DCPG, Racemate and R-enantiomer also available.

Technical Data

M.Wt:
239.18
Formula:
C10H9NO6
Solubility:
Soluble to 100 mM in water
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
201730-11-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for (S)-3,4-DCPG

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