Competitive antagonist at group I mGlu1a/1a
receptors, mixed effect at mGlu5a/5b
receptors; agonist at group II metabotropic glutamate receptors. (RS)-4-Carboxy-3-hydroxyphenylglycine
(Cat. No. 0310) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.
Sekiyama et al.
Br. J. Pharmacol., 1996;117:1493
Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects mGluR1α and mGluR5a subtypes.
Kingston et al.
Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system
Birse et al.
Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types.
Hayashi et al.
The citations listed below are publications that use Tocris products. Selected citations for (S)-4-Carboxy-3-hydroxyphenylglycine include:
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