(S)-(-)-Carbidopa

Catalog # Availability Size / Price Qty
0455/25
(S)-(-)-Carbidopa | CAS No. 28860-95-9 | Decarboxylase Inhibitors
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Description: Aromatic L-amino acid decarboxylase inhibitor

Chemical Name: (S)-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid

Purity: ≥99%

Product Details
Reviews (1)

Biological Activity

(S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism.

Technical Data

M.Wt:
226.23
Formula:
C10H14N2O4
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
28860-95-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Carbidopa inhibition of aromatic L-amino acid decarboxylase in rat brain capilliaries.
    Cheng et al.
    FASEB J., 1992;6:A1589
  2. L-Dopa infusion experiments in combination with the L-dopa decarboxylase inhibitors benserazide and carb. - L-dopa metabolism and neuroendocrinological effects.
    Kopfhammer et al.
    Pharmacopsychiatry, 1985;18:143

Product Datasheets

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Carbidopa was used to understand it's effect on brain DDC conversion of levodopa/L-DOPA to dopamine
By Provs Pantha on 08/16/2019
Application: Species: Human

Carbidopa acts as a peripheral DDC inhibitor, and carbidopa was used to understand it's effect on brain DDC conversion of levodopa/L-DOPA to dopamine.


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