(S)-Methylisothiourea sulfate
Biological Activity
(S)-Methylisothiourea sulfate is a highly selective, potent competitive inhibitor of iNOS.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat.
Iuvone et al.
Br.J.Pharmacol., 1997;121:1637 -
Isothioureas - potent inhibitors of nitric oxide synthases with variable isoform selectivity.
Southan et al.
Br.J.Pharmacol., 1995;114:510
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Citations for (S)-Methylisothiourea sulfate
The citations listed below are publications that use Tocris products. Selected citations for (S)-Methylisothiourea sulfate include:
2 Citations: Showing 1 - 2
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Protein kinase C-dependent mitochondrial translocation of proapoptotic protein Bax on activation of inducible nitric-oxide synthase in rostral ventrolateral medulla mediates cardiovascular depression during experimental endotoxemia.
Authors: Chan Et al.
Mol Pharmacol 2007;71:1129
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Differential contributions of nitric oxide synthase isoforms at hippocampal formation to negative feedback regulation of penile erection in the rat.
Authors: Chang Et al.
Br J Pharmacol 2002;136:43313
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