(S)-PFI 2 hydrochloride

Tocris Bioscience | Catalog # 5400

Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
Tocris Bioscience

Key Product Details

Description

Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
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Product Description

(S)-PFI 2 hydrochloride is a negative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer.

Active Analog also available.

Licensing Information

This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the (R)-PFI 2 probe summary on the SGC website.

Product Specifications for (S)-PFI 2 hydrochloride

Molecular Weight

535.98

Formula

C23H25F4N3O3S.HCl

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

8-Fluoro-1,2,3,4-tetrahydro-N-[(1S)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride

CAS Number

1627607-88-8

PubChem ID

91691132

InChI Key

ZADKZNVAJGEFLC-BOXHHOBZSA-N

SMILES

O=C(N4CCCC4)[C@H](CC3=CC=CC(C(F)(F)F)=C3)NS(C2=CC1=C(C(F)=C2)CNCC1)(=O)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 53.6 100
Ethanol 10.72 20

Preparing Stock Solutions for (S)-PFI 2 hydrochloride

The following data is based on the product molecular weight 535.98.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.87 mL 9.33 mL 18.66 mL
5 mM 0.37 mL 1.87 mL 3.73 mL
10 mM 0.19 mL 0.93 mL 1.87 mL
50 mM 0.04 mL 0.19 mL 0.37 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (S)-PFI 2 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (S)-PFI 2 hydrochloride

For research use only

Related Research Areas

Epigenetics

Citations for (S)-PFI 2 hydrochloride

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