(S)-SNAP 5114

  ( 5 citations )    
Product Datasheet
Catalog Number:1561
Chemical Name:1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid
Product Details
Citations (5)
Reviews
Biological Activity
GABA transport inhibitor, showing selectivity for GAT-3 and GAT-2 (IC50 values are 5, 21 and 388 μM for hGAT-3, rGAT-2 and hGAT-1 respectively). Increases thalamic GABA levels and is an anticonvulsant following systemic administration in vivo.
Technical Data
  • M.Wt:
    505.61
  • Formula:
    C30H35NO6
  • Solubility:
    Soluble to 50 mM in ethanol and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    157604-55-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for (S)-SNAP 5114 include:

5 Citations: Showing 1 - 5
Filter your results:

  1. Context-Dependent Modulation of GABAAR-Mediated Tonic Currents.
    Authors: Patel Et al.
    J Physiol  2016;36:607
  2. Recurrent seizure-like events are associated with coupled astroglial synchronization.
    Authors: Kékesi Et al.
    J Neurosci  2015;9:215
  3. A functional role for both -aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus.
    Authors: Kersanté Et al.
    J Neurophysiol  2013;591:2429
  4. Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus.
    Authors: Herd Et al.
    J Neurosci  2013;33:14850
  5. GAT-3 transporters regulate inhibition in the neocortex.
    Authors: Kinney
    Mol Pain  2005;94:4533

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used (S)-SNAP 5114?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee