(S)-WAY 100135 dihydrochloride

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1253/10
1253/50
Cat.No. 1253 - (S)-WAY 100135 dihydrochloride | C24H33N3O2.2HCl | CAS No. 149007-54-5
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Description: Potent and selective 5-HT1A antagonist

Chemical Name: (S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide dihydrochloride

Purity: ≥99%

Product Details
Citations (7)
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Biological Activity

Potent, selective 5-HT1A receptor antagonist (IC50 = 15 nM). Selective over 5-HT1B, 1C, 2,α1, α2 and D2 receptors (IC50 > 1000 nM). Centrally active on systemic administration.

Technical Data

M.Wt:
468.47
Formula:
C24H33N3O2.2HCl
Solubility:
Soluble to 100 mM in DMSO and to 5 mM in water with gentle warming and to 10 mM in water with sonica
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
149007-54-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of Wyeth-Ayerst Research, US Patent 4,988,814

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