S100A1 Antibody Pair [HRP]

Novus Biologicals | Catalog # NBP2-79557

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Assay Type

Sandwich ELISA

Assay Range

31.25-2000 pg/ml (example only; lot dependent)

Sensitivity

31.25 pg/ml (example only; lot dependent)

Reactivity

Mouse
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Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Mouse S100A1.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for S100A1 Antibody Pair [HRP]

Sandwich ELISA: S100A1 Antibody Pair [HRP] [NBP2-79557] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for S100A1 Antibody Pair [HRP]

  • Rabbit Monoclonal Capture Antibody: (Catalog # NBP2-90504)
  • Rabbit Monoclonal Detection Antibody (HRP-conjugated): (Catalog # NBP2-90505)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: S100A1

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.

Long Name

S100 Calcium Binding Protein A1

Alternate Names

protein S100-A1, S100 alpha, S100 calcium binding protein A1, S100 calcium-binding protein A1S100, S-100 protein alpha chain, S-100 protein subunit alpha, S100 protein, alpha polypeptide, S100A, S100-alpha

Gene Symbol

S100A1

Additional S100A1 Products

Product Documents for S100A1 Antibody Pair [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for S100A1 Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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