Potent and selective 5-HT2B
receptor antagonist (pA2
= 7.95). Displays ≥ 135-fold selectivity over 5-HT2C
= 5.82), 5-HT2A
< 5.2), 5-HT1A
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Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease.
Ebrahimkhani et al.
The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2B) receptor gene products: comparison with 5-HT2A and 5-HT2C receptors.
Bonhaus et al.
Further evidence that 5-HT-induced relaxation of pig pulmonary artery is mediated by endothelial 5-HT2B receptors.
Glusa and Pertz
N-(1-Methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea: a novel, high-affinity 5-HT2B receptor antagonist.
Forbes et al.
The citations listed below are publications that use Tocris products. Selected citations for SB 204741 include:
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