Selective non-peptide CGRP1
antagonist. Inhibits [125
I]CGRP binding and CGRP-activated adenylyl cyclase stimulation in SK-N-MC cell membranes (IC50
values are 0.24 and 0.83 nM respectively).
Soluble to 50 mM in DMSO
Store at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold with the permission of GlaxoSmithKline.
Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist.
Aiyar et al.