You are here

Home » TRPV Antagonists » SB 452533


SB 452533

  ( 1 citations )    
Product Datasheet
Catalog Number:3265
Chemical Name:N-(2-Bromophenyl)-N'-[2-[ethyl(3-methylphenyl)amino]ethyl]-urea
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Potent TRPV1 antagonist against capsaicin (pKb = 7.7), noxious heat and acid-mediated (pIC50 = 7.0) receptor activation (pKi = 6.22 at the recombinant hTRPV1 receptor). Exhibits analgesic properties.
Technical Data
  • M.Wt:
    376.29
  • Formula:
    C18H22BrN3O
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    459429-39-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes only under agreement from GlaxoSmithKline
Product Datasheets
SDS
COA view current batch
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SB 452533 include:

1 Citations: Showing 1 - 1

  1. Measurement of Ensemble TRPV1 Ion Channel Currents Using Droplet Bilayers.
    Authors: Vijayvergiya Et al.
    Mol Pain  2015;10:e0141366

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used SB 452533?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note: No more than 500 mg per individual per year to be sold without prior permission from the licence holder.
Contact Us to Order
reload

Feedback

Customer Information
You May Also Like
 
Rat Vanilloid R1/TRPV1 (NP_114188) VersaClone cDNA
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee