Chemical Name: 8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-acetylhydrazide
Biological ActivitySC 19220 is a selective EP1 receptor antagonist (IC50 = 6.7 μM for inhibition of [3H]-PGE2 binding to EP1 transfected COS cells).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Receptor subtypes involved in dual effects induced by prostaglandin E2 in circular smooth muscle from dog colon.
Botella et al.
Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.
Funk et al.
Dibenzoxazepine hydrazides as prostaglandin antagonists.
Intra-Science Chem.Rept., 1972;6:1
Citation for SC 19220
The citations listed below are publications that use Tocris products. Selected citations for SC 19220 include:
1 Citation: Showing 1 - 1
Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland.
Authors: Passafaro Et al.
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VersaClone cDNA Plasmids
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