receptor antagonist (IC50
= 6.7 μ
M for inhibition of [3
binding to EP1
transfected COS cells).
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All Tocris products are intended for laboratory research use only.
Receptor subtypes involved in dual effects induced by prostaglandin E2 in circular smooth muscle from dog colon.
Botella et al.
Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.
Funk et al.
Dibenzoxazepine hydrazides as prostaglandin antagonists.
Intra-Science Chem.Rept., 1972;6:1
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