Chemical Name: 8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid hydrazide
Biological ActivityPotent EP1 prostanoid receptor antagonist (Ki = 13.8 nM). Displays analgesic properties in vivo.
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A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture
Durocher et al.
8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid,2-[3-[2-(furanylmethyl)thio]-1-oxopropyl]hydrazide (SC-51322): A potent PGE2 antagonist and analgesic.
Hallinan et al.
Citation for SC 51322
The citations listed below are publications that use Tocris products. Selected citations for SC 51322 include:
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Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells.
Authors: Guillem-Llobat Et al.
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VersaClone cDNA Plasmids
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in vivo survival assay