SC 51322

Catalog # Availability Size / Price Qty
2791/10
2791/50
SC 51322 | CAS No. 146032-79-3 | Prostanoid Receptor Antagonists
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Description: Potent EP1 receptor antagonist

Chemical Name: 8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid hydrazide

Purity: ≥98%

Product Details
Citations (1)
Supplemental Products
Reviews (1)

Biological Activity

Potent EP1 prostanoid receptor antagonist (Ki = 13.8 nM). Displays analgesic properties in vivo.

Technical Data

M.Wt:
457.93
Formula:
C22H20ClN3O4S
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
146032-79-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Background References

  1. A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture
    Durocher et al.
    Anal.Biochem., 2000;284:316
  2. 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid,2-[3-[2-(furanylmethyl)thio]-1-oxopropyl]hydrazide (SC-51322): A potent PGE2 antagonist and analgesic.
    Hallinan et al.
    Bioorg.Med.Chem.Lett., 1994;4:509

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Citation for SC 51322

The citations listed below are publications that use Tocris products. Selected citations for SC 51322 include:

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SC 51322
By Anonymous on 05/31/2017
Application:

in vivo survival assay


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