SC 560

  ( 1 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:1550
Chemical Name:5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
Product Details
Citations (1)
Reviews
Biological Activity
Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.009 and 6.3 μM for COX-1 and COX-2 respectively). Inhibits COX-1-derived platelet thromboxane B2, gastric PGE2 and dermal PDE2 production. Significantly reduces ovarian surface epithelial tumor growth in vivo. Orally active.
Technical Data
  • M.Wt:
    352.74
  • Formula:
    C17H12ClF3N2O
  • Solubility:
    Soluble to 100 mM in DMSO and to 25 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    188817-13-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SC 560 include:

1 Citations: Showing 1 - 1

  1. Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice.
    Authors: Fritz Et al.
    J Clin Invest  2016;126:695

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Average Rating: 5 (Based on 1 review)

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