SC 57461A

Catalog # Availability Size / Price Qty
3107/10
3107/50
Cat.No. 3107 - SC 57461A | C20H25NO3.HCl | CAS No. 423169-68-0
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Description: Selective inhibitor of LTA4 hydrolase

Chemical Name: N-methyl-N-[3-[4-(phenylmethyl)phenoxy]propyl]-β-alanine hydrochloride

Purity: ≥98%

Product Details
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Biological Activity

Potent and selective inhibitor of LTA4 hydrolase. Does not inhibit other enzymes of the arachidonic acid cascade including COX-1, COX-2, LTC4 synthase and 5-lipoxygenase. Potently inhibits LTB4 production in whole blood (IC50 = 49 nM). Orally active.

Technical Data

M.Wt:
363.88
Formula:
C20H25NO3.HCl
Solubility:
Soluble to 25 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
423169-68-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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