SD 2590 hydrochloride

Catalog # Availability Size / Price Qty
4775/10
4775/50
Cat.No. 4775 - SD 2590 hydrochloride | C22H25F3N2O7S.HCl | CAS No. 226395-93-3
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Description: Potent MMP inhibitor
Alternative Names: SC 78080

Chemical Name: N-Hydroxy-1-(2-methoxyethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl]-4-piperidinecarboxamide hydrochloride

Purity: ≥98%

Product Details
Reviews

Biological Activity

Potent MMP inhibitor (IC50 values are <0.1, <0.1, 0.18, 1.7, 13 and 28.7 nM for MMP-2, -13, -9, -8, -14 and -3 respectively). Exhibits 100,000-fold selectivity for MMP-2 and -13 over MMP-1. Reduces left ventricular dilation in a myocardial infarction rat model. Orally bioavailable.

Technical Data

M.Wt:
554.96
Formula:
C22H25F3N2O7S.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
226395-93-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc

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