SDZ WAG 994

Catalog # Availability Size / Price Qty
2465/10
SDZ WAG 994 | CAS No. 130714-47-5 | Adenosine A1 Receptor Agonists
1 Image
Description: Potent, selective A1 agonist

Chemical Name: N-Cyclohexyl-2'-O-methyladenosine

Purity: ≥99%

Product Details
Supplemental Products
Reviews

Biological Activity

Potent and selective A1 adenosine receptor agonist (Ki values are 23, > 10000 and 25000 nM for A1, A2A and A2B receptors respectively). Causes a sustained fall in blood pressure and heart rate in spontaneous hypertensive rats and inhibits adenosine deaminase-stimulated lipolysis in rat adipocytes (Ki = 8 nM).

Technical Data

M.Wt:
363.41
Formula:
C17H25N5O4
Solubility:
Soluble to 100 mM in 1.1eq. NaOH and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
130714-47-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Adenosine receptors as therapeutic targets.
    Jacobson and Gao
    Nat.Rev.Drug Discov., 2006;5:247
  2. Hypoglycemic and hypotensive effects of 6-cyclohexyl-2'-O-methyl-adenosine, an adenosine A1 receptor agonist, in spontaneous hypertensive rat complicated with hyperglycemia.
    Ishikawa et al.
    Diabetes Res.Clin.Pract., 1998;39:3
  3. General pharmacology of SDZ WAG 994, a potent selective and orally active adenosine A1 receptor agonist.
    Wagner et al.
    Drug Dev.Res., 1995;34:276

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for SDZ WAG 994

There are currently no reviews for this product. Be the first to review SDZ WAG 994 and earn rewards!

Have you used SDZ WAG 994?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.