SECISBP2 Antibody

Novus Biologicals | Catalog # NB100-53795

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Canine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Peptide ELISA, Immunoprecipitation, Knockdown Validated

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all SECISBP2 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KERQERKQRLQEN corresponding to internal region according to NP_076982.3.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Novus Biologicals Goat SECISBP2 Antibody (NB100-53795) is a polyclonal antibody validated for use in IHC, WB, ELISA and IP. Anti-SECISBP2 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for SECISBP2 Antibody

Immunohistochemistry-Paraffin: SECISBP2 Antibody [NB100-53795]

Immunohistochemistry-Paraffin: SECISBP2 Antibody [NB100-53795]

Immunohistochemistry-Paraffin: SECISBP2 Antibody [NB100-53795] - Staining of paraffin embedded Human Testis. Antibody at 3 ug/mL. Microwaved antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

Applications for SECISBP2 Antibody

Application
Recommended Usage

Immunohistochemistry

3 ug/mL

Immunohistochemistry-Paraffin

3 ug/mL

Peptide ELISA

Detection limit 1:64000

Western Blot

0.1 - 0.3 ug/mL
Application Notes
ICC/IF successful usage for C33A cells is reported in scientific literature (PMID: 19004874).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SECISBP2

SECISBP2 is an RNA binding protein that interacts with the Sec insertion sequence (SECIS) element in selenoprotein mRNAs. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. Mutations in the SECISBP2 gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.

Alternate Names

DKFZp686C09169, SBP2SECIS-binding protein 2, SECIS binding protein 2, selenocysteine insertion sequence binding protein 2, selenocysteine insertion sequence-binding protein 2

Entrez Gene IDs

79048 (Human)

Gene Symbol

SECISBP2

UniProt

NP_076982.3 (Human)

Additional SECISBP2 Products

Product Documents for SECISBP2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for SECISBP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for SECISBP2 Antibody

Customer Reviews for SECISBP2 Antibody

There are currently no reviews for this product. Be the first to review SECISBP2 Antibody and earn rewards!

Have you used SECISBP2 Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies