Senktide

Name: Senktide
Brand: Tocris Bioscience
SKU: 1068
Price: 172 USD
Availability: InStock

Tocris Bioscience | Catalog # 1068

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Citations (76)

Product Documents

Tachykinin NK3 agonist

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Tachykinin NK3 agonist

View all NK3 Receptor Agonists »

Product Description

Senktide is a NK₃ tachykinin receptor agonist. Causes direct excitation of dopamine neurons; enhances dopaminergic function. Induces locomotor activity.

Product Specifications for Senktide

Molecular Weight

841.97

Formula

C₄₀H₅₅N₇O₁₁S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

106128-89-6

PubChem ID

90479751

InChI Key

UGXWLDUHYDFTIA-QKUYTOGTSA-N

SMILES

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC1=CC=C(C)C=C1)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(O)=O)NC(=O)CCC(O)=O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in PBS (pH 7.4)

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

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g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Concentration 1 (C1)

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Concentration 2 (C2)

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 76 publications citing the usage of this product.

Nordquist The tachykinin NK₃ receptor agonist senktide induces locomotor activity in male Mongolian gerbils. Eur.J.Pharmacol. 2008 PMID: 18930726
Renzetti Characterization of NK-3 binding sites in rat and guinea-pig cortical membranes by the selective ligand [³H]senktide. Neuropeptides 1991 PMID: 1712430
Keegan The selective NK receptor agonist senktide excites a subpopulation of DA-sensitive neurones in the rat substantia nigra pars compacta in vitro. Br.J.Pharmacol. 1992 PMID: 1375857

Product Documents for Senktide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Senktide

For research use only

Citations for Senktide

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