tachykinin receptor agonist. Causes direct excitation of dopamine neurons; enhances dopaminergic function. Induces locomotor activity.
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The selective NK receptor agonist senktide excites a subpopulation of dopamine-sensitive neurones in the rat substantia nigra pars compacta in vitro.
Keegan et al.
Characterization of NK-3 binding sites in rat and guinea-pig cortical membranes by the selective ligand [3H]senktide.
Renzetti et al.
The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils.
Nordquist et al.
The citations listed below are publications that use Tocris products. Selected citations for Senktide include:
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