Chemical Name: N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide
Biological ActivityPotent and selective CB2 receptor agonist (Ki values are 6.3 nM and 1.2 μM for CB2 and CB1 receptors respectively). Displays analgesic activity in the formalin test in mice.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo.
Pasquini et al.
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury.
Citation for SER 601
The citations listed below are publications that use Tocris products. Selected citations for SER 601 include:
1 Citation: Showing 1 - 1
Impaired Excitatory Neurotransmission in the Urinary Bladder from the Obese Zucker Rat: Role of Cannabinoid Receptors.
Authors: Blaha Et al.
PLoS One 2016;11:e0157424
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