Catalog Number: 3556
Alternate Names: COR 167
Chemical Name: N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide
Biological Activity
Potent and selective CB2 receptor agonist (Ki values are 6.3 nM and 1.2 μM for CB2 and CB1 receptors respectively). Displays analgesic activity in the formalin test in mice.
Technical Data
  • M.Wt:
    434.61
  • Formula:
    C28H38N2O2
  • Solubility:
    Soluble to 25 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    1048038-90-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo.
    Pasquini et al.
    J.Med.Chem., 2008;51:5075
  2. A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury.
    Contartese
    Pharmacol.Res., 2012;66:555

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