Chemical Name: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride
Biological ActivityPotent, orally active selective serotonin re-uptake inhibitor (SSRI); antidepressant.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotonin.
Koe et al.
Pharmacology of sertraline: a review.
Heym and Koe
Sertraline: a new antidepressant.
Doogan and Caillard
Citations for Sertraline hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Sertraline hydrochloride include:
3 Citations: Showing 1 - 3
Serotonin and Antidepressant SSRIs Inhibit Rat Neuroendocrine DA Neurons: Parallel Actions in the Lactotrophic Axis
Authors: Lyons Et al.
The journal of Neuroscience 2016;36:7392
Selective serotonin reuptake inhibitor exposure constricts the mouse ductus arteriosus in utero.
Authors: Hooper Et al.
Am J Physiol Heart Circ Physiol 2016;311:H572
Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation.
Authors: Pai Et al.
J Neurosci 2015;35:4366
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