Sertraline hydrochloride

Catalog # Availability Size / Price Qty
Sertraline hydrochloride | CAS No. 79559-97-0 | 5-HT Transporter Inhibitors
1 Image
Description: 5-HT reuptake inhibitor

Chemical Name: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride

Purity: ≥99%

Product Details
Citations (3)

Biological Activity

Sertraline is a potent and selective serotonin (5-HT) reuptake inhibitor (SSRI) that is an orally active antidepressant. Sertraline also decreases ergosterol biosynthesis and exhibits antifungal activity against Candida auris in vitro. Sertraline acts as an inhibitor of SHMT(serine hydroxymethyltransferase), inhibiting serine/glycine synthesis and proliferation of serine/glycine synthesis-dependent breast cancer cell lines in vitro and in vivo.

Technical Data

Soluble to 100 mM in DMSO and to 50 mM in ethanol
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Sertraline hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Sertraline hydrochloride include:

3 Citations: Showing 1 - 3


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Sertraline hydrochloride

There are currently no reviews for this product. Be the first to review Sertraline hydrochloride and earn rewards!

Have you used Sertraline hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.