SEW 2871

Catalog # Availability Size / Price Qty
2284/10
2284/50
Cat.No. 2284 - SEW 2871 | C20H10F6N2OS | CAS No. 256414-75-2
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Description: Cell-permeable, selective S1P1 receptor agonist

Chemical Name: 5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]1,2,4-oxadiazole

Purity: ≥99%

Product Details
Citations (5)
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Biological Activity

Novel, potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Activates S1P1 receptor with an EC50 of 13 nM, but does not activate S1P2, S1P3, S1P4 or S1P5 receptors at concentrations up to 10 μM. Cell-permeable and active in vivo.

Technical Data

M.Wt:
440.36
Formula:
C20H10F6N2OS
Solubility:
Soluble to 20 mM in DMSO and to 20 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
256414-75-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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