SGC AAK1 1

Catalog # Availability Size / Price Qty
6528/5
6528/25
Cat.No. 6528 - SGC AAK1 1 | C21H25N5O3S
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Description: AAK1 and BMP2K inhibitor; activates Wnt signaling

Chemical Name: N-(6-(3-((N,N-diethylsulfamoyl)amino)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

Adaptor-associated protein kinase 1 (AAK1) and BMP-2-inducible protein kinase (BMP2K) inhibitor (IC50 values are 233 nM and 1.48 μM for AAK1 and BMP2K, respectively). Inhibits AAK1-dependent phosphorylation of AP2M1. Activates Wnt signaling.

Technical Data

M.Wt:
427.52
Formula:
C21H25N5O3S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC-AAK1-1 probe summary on the SGC website.

Product Datasheets

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