Human SHP-1 ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) %CV 10 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) %CV 12 (example only; lot dependent)

Scientific Data Images for Human SHP-1 ELISA Kit (Colorimetric)

Kit Contents for Human SHP-1 ELISA Kit (Colorimetric)

• Detection Reagent A
• Detection Reagent B
• Diluent Buffer
• Instruction manual
• Plate sealer for 96 wells
• Pre-coated 96T strip plate
• Standard
• Stop Solution
• TMB Substrate
• Wash Buffer (30 x concentrate)

Preparation and Storage

Background: SHP-1

The SH2 domain-containing phosphatases, SHP-1 and SHP-2, are well-studied cytosolic tyrosine phosphatases that share many structural and regulatory features. They both have two tandem SH2 domains at the N-terminus, followed by a catalytic domain, and an inhibitory C-terminus. Despite their structural similarity, the enzymes appear to have different physiological roles and exhibit different expression patterns. SHP-1 is highly expressed in hematopoietic tissues, and in general has a negative impact on lymphocyte signaling. In contrast, SHP-2 is widely expressed, and in general promotes signaling pathways that lead to differentiation, cell growth, or migration.

Additional SHP-1 Products

• All Products for SHP-1
• SHP-1 ELISA Kits
• SHP-1 Lysates
• SHP-1 Primary Antibodies
• SHP-1 Proteins and Enzymes

Product Documents for Human SHP-1 ELISA Kit (Colorimetric)