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Shz 1

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Shz 1 | CAS No. 326886-05-9 | Compounds for Stem Cell Differentiation
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Description: Activator of early cardiac genes in pluripotent stem cells; induces differentiation in M-PBMCs

Chemical Name: 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide benzenesulfonic acid

Purity: ≥98%

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Biological Activity

Shz 1 is an activator of early cardiac genes (including Nkx2.5) in pluripotent stem cells. Induces phenotypic differentiation in human mobilized peripheral blood mononuclear cells. Enhances myocardial regenerative repair by stem cells in a rat myocardial cryoinjury model.

Technical Data

M.Wt:
355.21
Formula:
C13H11BrN2O3S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
326886-05-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Cardiogenic small molecules that enhance myocardial repair by stem cells.
    Sadek et al.
    Proc.Natl.Acad.Sci.U.S.A., 2008;105:6063

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