Chemical Name: 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide benzenesulfonic acid
Biological ActivityActivator of early cardiac genes (including Nkx2.5) in pluripotent stem cells. Induces phenotypic differentiation in human mobilized peripheral blood mononuclear cells. Enhances myocardial regenerative repair by stem cells in a rat myocardial cryoinjury model.
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Cardiogenic small molecules that enhance myocardial repair by stem cells.
Sadek et al.
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