Chemical Name: 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide benzenesulfonic acid
Biological ActivityShz 1 is an activator of early cardiac genes (including Nkx2.5) in pluripotent stem cells. Induces phenotypic differentiation in human mobilized peripheral blood mononuclear cells. Enhances myocardial regenerative repair by stem cells in a rat myocardial cryoinjury model.
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Cardiogenic small molecules that enhance myocardial repair by stem cells.
Sadek et al.
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