Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan-2-[[[2-[(2-ethylphenyl)amino]-2-oxoethyl]thio]carbonyl]hydrazide
Biological ActivityPotent and reversible human cathepsin L inhibitor (IC50 = 56 nM). Displays no inhibitory activity at cathepsin G. Antimalarial; inhibits leishmaniasis.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Kinetic characterization and molecular docking of a novel, potent and selective slow-binding inhibitor of human cathepsin L.
Shah et al.
Identification and synthesis of a unique thiocarbazate cathepsin L inhibitor.
Myers et al.
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